SA¹ú¼Ê´«Ã½

Tuesday 15 July 2025
Salisbury Foundation Trust

FOI_8687

Internal Reference Number: FOI_8687

Date Request Received: 03/06/2025 00:00:00

Date Request Replied To: 26/06/2025 00:00:00

This response was sent via: By Email

Request Summary: Oncology Breast Cancer

Request Category: Researcher



 
Question Number 1:
I am researching the incidence and treatment of breast cancer. I would greatly appreciate if you could answer the following questions

How many patients have been treated for breast cancer (any stage) in the past 3 months with the following systemic anti-cancer therapies:

• Abemaciclib + Aromatase Inhibitor (e.g. anastrazole, exemestane, letrozole)

• Abemaciclib + Fulvestrant

• Alpelisib + Fulvestrant

• Anthracycline (e.g. doxorubicin or epirubicin) + Cyclophosphamide

• Anthracycline (e.g. doxorubicin or epirubicin) + Cyclophosphamide + Paclitaxel

• Atezolizumab

• Capivasertib

• Capecitabine as a single agent

• Carboplatin + Paclitaxel

• Elacestrant

• Eribulin as a single agent or in combination

• Everolimus + Exemestane

• Fulvestrant as a single agent

• Palbociclib + Aromatase Inhibitor (e.g. anastrazole, exemestane, letrozole)

• Palbociclib + Fulvestrant

• Parp Inhibitors (Olaparib/Talazoparib)

• Pembrolizumab Monotherapy

• Anthracycline (e.g. doxorubicin or epirubicin) + Cyclophosphamide + Pembrolizumab

• Carboplatin + Paclitaxel + Pembrolizumab

• Pertuzumab (Perteja) + Trastuzumab (Herceptin)

• Phesgo (Pertuzumab + Trastuzumab in a single injection)

• Ribociclib + Aromatase Inhibitor (e.g. anastrazole, exemestane, letrozole)

• Ribociclib + Fulvestrant

• Sacituzumab Govitecan

• Taxane (e.g. docetaxel, paclitaxel, nab-paclitaxel) as a single agent

• Trastuzumab deruxtecan (Enhertu)

• Trastuzumab (Herceptin) as a single agent or in combination with Paclitaxel

• Trastuzumab emtansine (Kadcyla)

• Any other active systemic anti-cancer therapy

• Aromatase Inhibitor as a single agent

 
Answer To Question 1:
• Abemaciclib + Aromatase Inhibitor (e.g. anastrazole, exemestane, letrozole) - 30

• Abemaciclib + Fulvestrant - 6

• Alpelisib + Fulvestrant - <5

• Anthracycline (e.g. doxorubicin or epirubicin) + Cyclophosphamide - <5

• Anthracycline (e.g. doxorubicin or epirubicin) + Cyclophosphamide + Paclitaxel - 0

• Atezolizumab - 0

• Capivasertib - <5

• Capecitabine as a single agent - 10

• Carboplatin + Paclitaxel - <5

• Elacestrant - <5

• Eribulin as a single agent or in combination - <5

• Everolimus + Exemestane - <5

• Fulvestrant as a single agent - 0

• Palbociclib + Aromatase Inhibitor (e.g. anastrazole, exemestane, letrozole) - 25

• Palbociclib + Fulvestrant - <5

• Parp Inhibitors (Olaparib/Talazoparib) - 0

• Pembrolizumab Monotherapy - <5

• Anthracycline (e.g. doxorubicin or epirubicin) + Cyclophosphamide + Pembrolizumab - <5

• Carboplatin + Paclitaxel + Pembrolizumab - 0

• Pertuzumab (Perteja) + Trastuzumab (Herceptin) - <5

• Phesgo (Pertuzumab + Trastuzumab in a single injection) - 21

• Ribociclib + Aromatase Inhibitor (e.g. anastrazole, exemestane, letrozole) - 17

• Ribociclib + Fulvestrant - <5

• Sacituzumab Govitecan - 7

• Taxane (e.g. docetaxel, paclitaxel, nab-paclitaxel) as a single agent - <5

• Trastuzumab deruxtecan (Enhertu) - 5

• Trastuzumab (Herceptin) as a single agent or in combination with Paclitaxel - 11

• Trastuzumab emtansine (Kadcyla) - <5

• Any other active systemic anti-cancer therapy - 13

• Aromatase Inhibitor as a single agent - can’t answer as single agent not prescribed on Aria and patients would get from the GP.
 
Question Number 2:
How many patients have been treated for metastatic breast cancer in the past 3 months with the following systemic anti-cancer therapies:

• Phesgo (Pertuzumab + Trastuzumab in a single injection)

• Pertuzumab (Perteja) + Trastuzumab (Herceptin)

• Trastuzumab (Herceptin) as a single agent or in combination with Paclitaxel

• Trastuzumab deruxtecan (Enhertu)

• Trastuzumab emtansine (Kadcyla)

• Abemaciclib + Aromatase Inhibitor (e.g. anastrazole, exemestane, letrozole)

• Abemaciclib + Fulvestrant

• Ribociclib + Aromatase Inhibitor (e.g. anastrazole, exemestane, letrozole)

• Ribociclib + Fulvestrant

• Capecitabine as a single agent

• Carboplatin + Paclitaxel

• Carboplatin + Paclitaxel + Pembrolizumab
 
Answer To Question 2:
• Phesgo (Pertuzumab + Trastuzumab in a single injection) - 12

• Pertuzumab (Perteja) + Trastuzumab (Herceptin) - <5

• Trastuzumab (Herceptin) as a single agent or in combination with Paclitaxel - 5

• Trastuzumab deruxtecan (Enhertu) - 5

• Trastuzumab emtansine (Kadcyla) - 0

• Abemaciclib + Aromatase Inhibitor (e.g. anastrazole, exemestane, letrozole) - 6

• Abemaciclib + Fulvestrant - 6

• Ribociclib + Aromatase Inhibitor (e.g. anastrazole, exemestane, letrozole) - 16

• Ribociclib + Fulvestrant - <5

• Capecitabine as a single agent - 11

• Carboplatin + Paclitaxel - 0

• Carboplatin + Paclitaxel + Pembrolizumab - 0
 
Question Number 3:
Does your trust participate in any Clinical trials for breast cancer? If so, please provide the name of each trial, and the number of patients taking part.
 
Answer To Question 3:
The answers to Q3 are in the attached document.

To accompany this answer to question 3 please also see the documents listed below:

 FOI 8687 - Q3.pdf
Please see Attachments:
 
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