SA¹ú¼Ê´«Ã½

Friday 09 May 2025
Salisbury Foundation Trust

FOI_8399

Internal Reference Number: FOI_8399

Date Request Received: 23/01/2025 00:00:00

Date Request Replied To: 21/02/2025 00:00:00

This response was sent via: By Email

Request Summary: Diffuse Large B Cell Lymphoma (BLBCL)

Request Category: Private Individuals

 
Question Number 1:
In the last 6 months, how many patients have been diagnosed with Diffuse Large B Cell Lymphoma (DLBCL)?


Of these patients, how many commenced treatment at your trust within the last 6 months?
 
Answer To Question 1:
Q1. Total patients diagnosed in last 6 months <= 5, of those total patients treated <=5

Pharmacy: <5 patients started chemo in last 6 months
 
Question Number 2:
In the last 6 months, how many patients have you treated for Diffuse Large B Cell Lymphoma (DLBCL) with the following treatments:

R-CHOP (rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine and prednisolone)

R-mini-CHOP (rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine and prednisolone)

Pola-BR (polatuzumab vedotin with rituximab and bendamustine)

Pola-R-CHP (Polatuzumab vedotin with rituximab, cyclophosphamide, doxorubicin hydrochloride, and prednisolone)

R-CODOX-M (rituximab, cyclophosphamide, vincristine, doxorubicin and methotrexate)

R-IVAC (rituximab, ifosfamide, etoposide and cytarabine)

R-GCVP (Rituximab, gemcitabine, cyclophosphamide, vincristine, prednisolone)

(DA)-EPOCH +/-R (Prednisolone, doxorubicin, vincristine, etoposide, cyclophosphamide, rituximab)

R-GemOX (rituximab, gemcitabine and oxaliplatin)

Axicabtagene ciloleucel

Tisagenlecleucel

Epcoritamab

Loncastuximab tesirine

Glofitamab

Any other SACT

Stem cell transplant or bone marrow transplant (autologous or allogeneic)
 
Answer To Question 2:
Q2. Any other SACT <= 5, R-CHOP/R-mini-CHOP <=5

Pharmacy:

RCHOP- >5 patients
R-mini-CHOP- >5 patients
Pola-BR- <5 patients
Pola-R-CHP- 5 patients
R-Gem-Ox- <5 patients
Epcoritamab <5 patients
Any other SACT- <5 patients

All other responses for Q2 are zero
 
Question Number 3:
In the last 6 months, how many patients have received the following 2nd line treatments for Diffuse Large B Cell Lymphoma (DLBCL):

Axicabtagene ciloleucel (Yescarta)

Tisagenlecleucel

Pola-BR (polatuzumab vedotin with rituximab and bendamustine)

R-GemOX (rituximab, gemcitabine and oxaliplatin)

Stem cell transplant or bone marrow transplant (autologous or allogeneic)

Any other treatments

 
Answer To Question 3:
Pharmacy:
Pol-BR- <5 patients
R-Gem-OX – <5 patients
Any other SACT – <5 patients
Transplants would go elsewhere so zero for response to all other questions
 
Question Number 4:
In the last 6 months, how many patients has the Trust has treated for 3rd line Diffuse Large B Cell Lymphoma (BLBCL)?
 
Answer To Question 4:
Q4. Unable to answer this as we are unable to distinguish 3rd line Diffuse Large B Cell Lymphoma (BLBCL) using a different ICD-10 diagnosis code to that used to answer Q1.

Pharmacy: <5 patients
 
Question Number 5:
In the last 6 months, how many patients have you referred to other trusts for the treatment of Diffuse Large B Cell Lymphoma (DLBCL) for the following treatments:

CAR-T Therapy (E.g. Axicabtagene ciloleucel)

Stem cell transplant or bone marrow transplant (autologous or allogeneic)

Any other treatment
 
Answer To Question 5:
CAR-T Therapy (E.g. Axicabtagene ciloleucel) - <5 referrals

Stem cell transplant or bone marrow transplant (autologous or allogeneic) - 0 referrals

Any other treatment - 0 referrals
 
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